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KMID : 1038120210540040555
Clinical Endoscopy
2021 Volume.54 No. 4 p.555 ~ p.562
Diode Laser-Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection?
Jung Yun-Ho

Baik Gwang-Ho
Ko Weon-Jin
Ko Bong-Min
Kim Seong-Hwan
Jang Jin-Seok
Jang Jae-Young
Lee Wan-Sik
Cho Young-Kwan
Lim Sun-Gyo
Moon Hee-Seok
Yoo In-Kyung
Cho Joo-Young
Abstract
Background/Aims: A new medical fiber-guided diode laser system (FDLS) is expected to offer high-precision cutting with simultaneous hemostasis. Thus, this study aimed to evaluate the feasibility of using the 1,940-nm FDLS to perform endoscopic submucosal dissection (ESD) in the gastrointestinal tract of an animal model.

Methods: In this prospective animal pilot study, gastric and colorectal ESD using the FDLS was performed in ex vivo and in vivo porcine models. The completeness of en bloc resection, the procedure time, intraprocedural bleeding, histological injuries to the muscularis propria (MP) layer, and perforation were assessed.

Results: The en bloc resection and perforation rates in the ex vivo study were 100% (10/10) and 10% (1/10), respectively; those in the in vivo study were 100% (4/4) and 0% for gastric ESD and 100% (4/4) and 25% (1/4) for rectal ESD, respectively. Deep MP layer injuries tended to occur more frequently in the rectal than in the gastric ESD cases, and no intraprocedural bleeding occurred in either group.

Conclusions: The 1,940-nm FDLS was capable of yielding high en bloc resection rates without intraprocedural bleeding during gastric and colorectal ESD in animal models.
KEYWORD
Endoscopic mucosal resection, Hemostasis, Lasers, Perforation
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